Allogenic bone marrow transplantation: current status and future directions
نویسندگان
چکیده
منابع مشابه
Allogeneic Bone Marrow Transplantation: Current Status and Future Directions
THE LAST DECADE, marrow transplantation been shown to provide a means for curative of a number of lethal congenital and disorders of the hematopoietic and lymphoid Marrow transplantation is the treatment of aplastic anemia and has emerged as a highly approach to the treatment of high-risk leukemia, particularly when applied to in remission early in the course of their Graft-versus-host disease ...
متن کاملALLOGENIC BONE MARROW TRANSPLANTATION IN APLASTIC ANEMIA
Eighteen patients, twelve men and six women, with aplastic anemia underwent allogenic bone marrow transplantation (BMT) from HLA-matched siblings during the period of 1990 to 1996. The conditioning regimen was cyclophosphamide with or without busulfan, depending on the cause of aplasia. Antilymphocyte globulin (ALG) and cyclosporine were used for rejection and acute GVHD prophylaxis, respe...
متن کامل[Allogenic bone marrow transplantation].
Allogeneic bone marrow transplantation (BMT) after high-dose, marrow-ablative chemoradiotherapy has been established as the treatment of choice for various hematologic, neoplastic, and congenital disorders. The most common type of marrow graft is an allogeneic one from a sibling donor who has compatible human leukocyte antigen (HLA). Only 30% of patients requiring allogeneic BMT have an HLA-com...
متن کاملBone marrow transplantation in acute leukemia: current status and future directions.
Bone marrow transplantation is an experimental approach to the treatment of patients with acute leukemia, aplastic anemia, and other neoplastic and genetic diseases. To date, long-term disease-free survival has been achieved in a small proportion of carefully selected patients with resistant acute leukemia. While results are not optimal, they are acceptable in late stage patients where there ar...
متن کاملCurrent issues and future directions in marrow transplantation.
The use of allogeneic marrow transplantation as treatment for patients with various hematological diseases has increased in recent years [1-6]. A survey by the International Bone Marrow Transplantation Registry [7] estimated the number of transplants carried out through the year 1987 to be in the order of 20000, more than 10000 of these during the years of 1985 through 1987. Marrow transplantat...
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ژورنال
عنوان ژورنال: Blood
سال: 1983
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v62.5.941.941